Glucocorticoid secretion involves an evolutionary tradeoff: it has protective effects during an ongoing physical stressor but can produce adverse long-term consequences when secretion is excessive.
Sources
- Glucocorticoids, the evolution of the stress-response, and ... - PubMed (pubmed.ncbi.nlm.nih.gov)
- https://www.sciencedirect.com/science/article/pii/S235228952100028X (sciencedirect.com)
- https://www.nature.com/articles/1395453 (nature.com)
- https://www.endocrinology.org/endocrinologist/130-winter18/features/glucocorticoids-restoring-balance-during-stress/ (endocrinology.org)
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